Association between long-term orthokeratology responses and corneal biomechanics.

作者: Andrew K. C. Lam , Ying Hon , Stanley Y. Y. Leung , Lu Shu-Ho , Jones Chong

DOI: 10.1038/S41598-019-49041-Z

关键词:

摘要: Myopia is very prevalent worldwide, especially among Asian populations. Orthokeratology a proven intervention to reduce myopia progression. The current study investigated association between baseline corneal biomechanics and orthokeratology responses, changes of from long-term orthokeratology. We fitted 59 adult subjects having −4.00D −5.00D with overnight Corneal was measured through dynamic bidirectional applanation (in terms hysteresis, CH resistance factor, CRF) indentation stiffness, S tangent modulus, E). Subjects poor responses had lower E (mean 0.474 MPa) than good 0.536 MPa). Successful for 6 months resulted in reducing (reduced by 5.8%) CRF 8.7%). stiffness stable, but showed an increasing trend. Among successful orthokeratology, higher greater reduction (Pearson correlation coefficient, r = 0.381, p = 0.02).

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