Prognostic significance of an interface pattern of central fibrosis and tumor cells in peripheral adenocarcinoma of the lung
作者： Katsushige Yamashiro , Shinya Yasuda , Atsushi Nagase , Tamotsu Hirata , Takayuki Nojima
DOI: 10.1016/0046-8177(95)90116-7
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摘要: Abstract Fifty-nine surgically resected pulmonary adenocarcinomas were histologically classified into four types (A, B, C, and D) according to the pattern of invasion, ie, extent invasive tumor cell growth in interface zone between alveoli replaced by cancer cells central region fibrosis (so-called “scar”). In A proliferate along alveolar walls without forming a frankly lesion. B lesions occupy less than 30% C more fibrosing area. Pattern D refers invasion bronchial lumen cells. The 59 tumors included 14 A, 12 16 17 D. 5-year survival rate for patients with was 100%, rates 64.2%, 30.0%, 11.8%, respectively. Each difference pairs curves statistically significant ( P
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