A case-control study of risk factors for canine atopic dermatitis among boxer, bullterrier and West Highland white terrier dogs in Sweden.

作者: Ane Nødtvedt , Kerstin Bergvall , Marie Sallander , Agneta Egenvall , Ulf Emanuelson

DOI: 10.1111/J.1365-3164.2007.00617.X

关键词:

摘要: Environmental and dietary risk factors for the development of canine atopic dermatitis (CAD) in high-risk breeds boxer, bullterrier West Highland white terrier were assessed a case–control study. A logistic regression model was developed to evaluate their relative importance 58 cases from 12 practices Sweden 61 unaffected controls, matched by breed year birth. The final included random error term ‘examining veterinarian’, as dogs same practice not considered independent. No effect gender, season birth, environment, vaccination or de-worming on odds developing CAD detected. main finding that feeding diet including noncommercial products bitch during lactation had protective her offspring; twice high among offspring bitches exposed home-made/noncommercial diets [95% confidence interval (CI) ratio: 1.2–3.8]. population attributable fraction home-made lactating estimated 0.4 (95% CI: 0.04–0.63). Randomized controlled clinical trials are needed further support potential role development.

参考文章(19)
N A Soter, F Kerdel, K H Rhodes, Comparative aspects of canine and human atopic dermatitis. Seminars in Veterinary Medicine and Surgery: Small Animal. ,vol. 2, pp. 166- 172 ,(1987)
T. WILLEMSE, BSAVA EDUCATION COMMITTEE COMMISSIONED ARTICLE Journal of Small Animal Practice. ,vol. 27, pp. 771- 778 ,(1986) , 10.1111/J.1748-5827.1986.TB02119.X
C.E Griffin, D.J DeBoer, The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis. Veterinary Immunology and Immunopathology. ,vol. 81, pp. 255- 269 ,(2001) , 10.1016/S0165-2427(01)00346-4
Ane Nødtvedt, Javier Guitian, Agneta Egenvall, Ulf Emanuelson, Dirk U. Pfeiffer, The spatial distribution of atopic dermatitis cases in a population of insured Swedish dogs. Preventive Veterinary Medicine. ,vol. 78, pp. 210- 222 ,(2007) , 10.1016/J.PREVETMED.2006.10.007
D. P. Strachan, Hay fever, hygiene, and household size. BMJ. ,vol. 299, pp. 1259- 1260 ,(1989) , 10.1136/BMJ.299.6710.1259
C. Flohr, D. Pascoe, H.C. Williams, Atopic dermatitis and the 'hygiene hypothesis': too clean to be true? British Journal of Dermatology. ,vol. 152, pp. 202- 216 ,(2005) , 10.1111/J.1365-2133.2004.06436.X
Stephen C. Shaw, James L. N. Wood, Julia Freeman, Janet D. Littlewood, Duncan Hannant, Estimation of heritability of atopic dermatitis in Labrador and Golden Retrievers. American Journal of Veterinary Research. ,vol. 65, pp. 1014- 1020 ,(2004) , 10.2460/AJVR.2004.65.1014
K. Stenshamn, E. Bongcam-Rudloff, N. Salmon Hillbertz, A. Nødtvedt, K. Bergvall, Å. Hedhammar, G. Andersson, Evaluation of kallikrein 7 as a disease-causing gene for canine atopic dermatitis using microsatellite-based association mapping. Animal Genetics. ,vol. 37, pp. 601- 603 ,(2006) , 10.1111/J.1365-2052.2006.01537.X
Syed Hasan Arshad, Primary prevention of asthma and allergy The Journal of Allergy and Clinical Immunology. ,vol. 116, pp. 3- 14 ,(2005) , 10.1016/J.JACI.2005.03.043