The functional role of beta subunits in oligomeric P-type ATPases.
作者： Käthi Geering
关键词:
摘要: Na,K-ATPase and gastric nongastric H,K-ATPases are the only P-type ATPases of higher organisms that oligomeric associated with a beta subunit, which is obligatory for expression function enzymes. Topogenesis studies suggest subunits have fundamental unique role in K+-transporting they facilitate correct membrane integration packing catalytic subunit these ATPases, necessary their resistance to cellular degradation, acquisition functional properties, routing cell surface. In addition this chaperone function, also participate determination intrinsic transport properties Na,K- H,K-ATPases. Increasing experimental evidence suggests assembly highly ordered, isoform-specific process, mediated by multiple interaction sites contribute coordinate, multistep process structural maturation
springer.com
sci-hub.se 参考文章(113)
M Hamrick, K.J. Renaud, D.M. Fambrough, Assembly of the extracellular domain of the Na,K-ATPase beta subunit with the alpha subunit. Analysis of beta subunit chimeras and carboxyl-terminal deletions. Journal of Biological Chemistry. ,vol. 268, pp. 24367- 24373 ,(1993) , 10.1016/S0021-9258(20)80535-3
S. Lutsenko, J.H. Kaplan, Molecular events in close proximity to the membrane associated with the binding of ligands to the Na,K-ATPase Journal of Biological Chemistry. ,vol. 269, pp. 4555- 4564 ,(1994) , 10.1016/S0021-9258(17)41813-8
Claudia Donnet, Elena Arystarkhova, Kathleen J. Sweadner, Thermal Denaturation of the Na,K-ATPase Provides Evidence for α-α Oligomeric Interaction and γ Subunit Association with the C-terminal Domain Journal of Biological Chemistry. ,vol. 276, pp. 7357- 7365 ,(2001) , 10.1074/JBC.M009131200
K Geering, D I Meyer, M P Paccolat, J P Kraehenbühl, B C Rossier, Membrane insertion of alpha- and beta-subunits of Na+,K+-ATPase. Journal of Biological Chemistry. ,vol. 260, pp. 5154- 5160 ,(1985) , 10.1016/S0021-9258(18)89192-X
K.J. Renaud, E.M. Inman, D.M. Fambrough, Cytoplasmic and transmembrane domain deletions of Na,K-ATPase beta-subunit. Effects on subunit assembly and intracellular transport. Journal of Biological Chemistry. ,vol. 266, pp. 20491- 20497 ,(1991) , 10.1016/S0021-9258(18)54951-6
J.D. Horisberger, P. Jaunin, M.A. Reuben, L.S. Lasater, D.C. Chow, J.G. Forte, G. Sachs, B.C. Rossier, K. Geering, The H,K-ATPase beta-subunit can act as a surrogate for the beta-subunit of Na,K-pumps. Journal of Biological Chemistry. ,vol. 266, pp. 19131- 19134 ,(1991) , 10.1016/S0021-9258(18)54968-1
M M Tamkun, D M Fambrough, The (Na+ + K+)-ATPase of chick sensory neurons. Studies on biosynthesis and intracellular transport. Journal of Biological Chemistry. ,vol. 261, pp. 1009- 1019 ,(1986) , 10.1016/S0021-9258(17)36045-3
P Jaunin, J D Horisberger, K Richter, P J Good, B C Rossier, K Geering, Processing, intracellular transport, and functional expression of endogenous and exogenous alpha-beta 3 Na,K-ATPase complexes in Xenopus oocytes. Journal of Biological Chemistry. ,vol. 267, pp. 577- 585 ,(1992) , 10.1016/S0021-9258(18)48533-X
G Schmalzing, S Kröner, M Schachner, S Gloor, The adhesion molecule on glia (AMOG/beta 2) and alpha 1 subunits assemble to functional sodium pumps in Xenopus oocytes. Journal of Biological Chemistry. ,vol. 267, pp. 20212- 20216 ,(1992) , 10.1016/S0021-9258(19)88688-X
K.A. Eakle, M.A. Kabalin, S.G. Wang, R.A. Farley, The influence of beta subunit structure on the stability of Na+/K(+)-ATPase complexes and interaction with K+. Journal of Biological Chemistry. ,vol. 269, pp. 6550- 6557 ,(1994) , 10.1016/S0021-9258(17)37407-0