The Replication Initiator Protein of P1 Is Activated by two E. coli Heat Shock Proteins, DnaJ and DnaK
作者： Sue Wickner , Joel Hoskins , Keith McKenney
DOI: 10.1007/978-3-642-76988-7_31
关键词:
摘要: Two E. coli heat shock proteins, DnaK (the hsp70 homolog) and DnaJ activate the specific DNA binding function of replication initiator protein, RepA, plasmid P1 by about 100-fold (Wickner et al., 1991). The activation is ATP-dependent DNA-independent. mechanism conversion RepA dimers to monomers monomer form binds with high affinity origin DNA. Treatment reversible chemical denaturants also converts simultaneously activates binding. Increasing protein concentration deactivates RepA.
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sci-hub.st 参考文章(19)
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