In vivo testing of canine prosthetic femoral components with HA-Ti ladder-type coating on vacuum plasma-sprayed Ti substrate
作者： Xian-lin Zeng , Jing-feng Li , Shu-hua Yang , Qi-xin Zheng , Zhen-wei Zou
DOI: 10.1007/S11596-013-1156-1
关键词:
摘要: The purpose of the present study was to observe structure and functional change bone-coating-prosthesis interface in vivo evaluate histocompatibility self-made prosthetic femoral components body degree their bonding with surrounding bone tissues as well stability. Six mature beagle dogs underwent bilateral hip replacement femur components. Three groups were established terms different coating prothesis (four joints each group): atmosphere (A) plasma-sprayed pure titanium (Ti) joint hydroxyapatite (HA) (HA+Ti+A group); vacuum (V) Ti HA (HA+Ti+V Ti-HA stepped (Ti+HAG+Ti+V group). functionally evaluated, subjected X-ray examination, biomechanics inspection, histological examination. As a result, imaging revealed all good location no dislocation found. Shear strength significantly higher Ti+HAG+Ti+V group than HA+Ti+V (P<0.05) HA+Ti+A at 28th week. Histological examination showed amount newborn more after 28 weeks. It suggested that TI-HA could improve capacity bone-prosthesis, enhance stability prosthesis, increase fixion because better growth. This new type biological material holds promises for application clinical practice.
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