Synthesis of vinca alkaloids and related compounds part 94. Epimerization of compounds with aspidospermane and D‐secoaspidospermane skeleton
作者： György Kalaus , Lajos Szabó , János Éles , Csaba Szántay , Imre Juhász
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摘要: The individual epimerization steps of vincadifformine (1), deethylvincadifformine isomers (2,3), their synthetic intermediates (4–13) as well that simpler compounds with D-secoaspidospermane skeleton (15–17) were studied a) in protic medium (boiling deuteroacetic acidic) and b) under reductive (with sodium borodeuteride boiling acetic acid, or borohydride acid) conditions.
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