Immunogenic properties of solubilized tumour antigen from an RNA virus-transformed neoplasm.
作者： LLOYD W. LAW , ETTORE APPELLA
DOI: 10.1038/243083A0
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摘要: NUMEROUS attempts have been made to solubilize tumour specific transplantation antigens (TSTA) of carcinogen-induced neoplasms and virus-specified (VSTA) from the cell membranes DNA RNA virus-induced neoplasms1–6. Usually, yields biologically active materials are low labile. Soluble antigenic obtained transplantable hepatomas1,2 purified by gel filtration were found limited biological activity. Although immunological specificity was preserved, assays used relatively precision. Tumour rejection, a major function both TSTA VSTA, not observed.
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sci-hub.se 参考文章(20)
R. W. Baldwin, Dorothy Glaves, Solubilization of tumour-specific antigen from plasma membrane of an aminoazo-dye-induced rat hepatoma. Clinical and Experimental Immunology. ,vol. 11, pp. 51- ,(1972)
J. L. McCoy, J. P. Glynn, A. Fefer, Cross-resistance to the Transplantation of Syngeneic Friend, Moloney, and Rauscher Virus-induced Tumors Cancer Research. ,vol. 28, pp. 434- 439 ,(1968)
R. C. Ting, Biological and Serological Properties of Viral Particles from a Nonproducer Rat Neoplasm Induced by Murine Sarcoma Virus (Moloney) Journal of Virology. ,vol. 2, pp. 865- 868 ,(1968) , 10.1128/JVI.2.9.865-868.1968
Alexander Fefer, Leroy Fass, Studies of Adoptive Chemoimmunotherapy of a Friend Virus-induced Lymphoma Cancer Research. ,vol. 32, pp. 997- 1001 ,(1972)
J. P. Glynn, A. R. Bianco, A. Goldin, Studies on Induced Resistance against Isotransplants of Virus-induced Leukemia Cancer Research. ,vol. 24, pp. 502- 508 ,(1964)
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
V. Klement, W. P. Rowe, J. W. Hartley, W. E. Pugh, Mixed culture cytopathogenicity: a new test for growth of murine leukemia viruses in tissue culture. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 63, pp. 753- 758 ,(1969) , 10.1073/PNAS.63.3.753
E. Appella, S. Strober, P. W. Wright, T. Fischetti, L. W. Law, Induction of immunological tolerance to soluble histocompatibility-2 antigens of mice. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 69, pp. 1858- 1862 ,(1972) , 10.1073/PNAS.69.7.1858
William Boyle, An extension of the 51cr-release assay for the estimation of mouse cytotoxins. Transplantation. ,vol. 6, pp. 761- 764 ,(1968) , 10.1097/00007890-196809000-00002
E. Carmack Holmes, Barry D. Kahan, Donald L. Morton, Soluble tumor-specific transplantation antigens from methylcholanthrens induced guinea pig sarcomas Cancer. ,vol. 25, pp. 373- 379 ,(1970) , 10.1002/1097-0142(197002)25:2<373::AID-CNCR2820250215>3.0.CO;2-L