Wilms Tumor-Susceptibility Loci

作者: Vicki Huff

DOI: 10.1007/978-1-4757-2381-6_9

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摘要: Nephroblastoma, or Wilms tumor (WT), is a childhood of the kidney that was described and characterized in several case reports reviews during 19th century. It acquired its commonly used eponym after Max published monograph on subject 1899. Occurring with frequency roughly 1 10,000 live births (Matsunaga, 1981; Breslow et al., 1983), WT one most common solid tumors children. Fortunately, it also successfully treated cancers; triple modality therapy surgery, chemotherapy, radiotherapy, overall 2-yr, disease-free survival rate now 85% (D’Angio 1989).

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