Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice.

作者: Xiaonan Han , Mitchell P Fink , Runkuan Yang , Russell L Delude , None

DOI: 10.1097/01.SHK.0000112346.38599.10

关键词:

摘要: ABSTRACTWe tested the hypothesis that increased production of nitric oxide (NO·) associated with lipopolysaccharide (LPS)-induced systemic inflammation leads to functionally significant alterations in expression and/or targeting key tight junction (TJ) proteins ileal and colonic epithelium

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