Methods Used to Study Apoptotic Cell Clearance

作者: Uriel Trahtemberg , Dror Mevorach

DOI: 10.1007/978-1-4020-9293-0_8

关键词:

摘要: The phagocytosis of dying cells is a complex process involving interactions between many molecules on the cell, phagocyte, and in micro-environment. Although much known subject, questions unknown variables remain under investigation. Knowledge appropriate methods for studying essential acquisition deeper understanding programmed cell death, phagocytosis, clearance, homeostasis. In this chapter we will define consensual vocabulary discuss general specific considerations regarding different models used to study clearance cells. second part describe further detail selected techniques protocols.

参考文章(185)
Adrian E. Morelli, Angus W. Thomson, Tolerogenic dendritic cells and the quest for transplant tolerance. Nature Reviews Immunology. ,vol. 7, pp. 610- 621 ,(2007) , 10.1038/NRI2132
Wei Xu, Anja Roos, Mohamed R. Daha, Cees van Kooten, Dendritic cell and macrophage subsets in the handling of dying cells. Immunobiology. ,vol. 211, pp. 567- 575 ,(2006) , 10.1016/J.IMBIO.2006.05.023
Lynda M. Stuart, R. Alan Ezekowitz, Phagocytosis and comparative innate immunity: learning on the fly. Nature Reviews Immunology. ,vol. 8, pp. 131- 141 ,(2008) , 10.1038/NRI2240
J. F. Evers, S. Schmitt, M. Sibila, C. Duch, Progress in functional neuroanatomy: precise automatic geometric reconstruction of neuronal morphology from confocal image stacks. Journal of Neurophysiology. ,vol. 93, pp. 2331- 2342 ,(2005) , 10.1152/JN.00761.2004
Piotr Smolewski, Jerzy Grabarek, Brian W. Lee, Gary L. Johnson, Zbigniew Darzynkiewicz, Kinetics of HL-60 cell entry to apoptosis during treatment with TNF-? or camptothecin assayed by the stathmo-apoptosis method Cytometry. ,vol. 47, pp. 143- 149 ,(2002) , 10.1002/CYTO.10062
Eric S Witze, William M Old, Katheryn A Resing, Natalie G Ahn, Mapping protein post-translational modifications with mass spectrometry Nature Methods. ,vol. 4, pp. 798- 806 ,(2007) , 10.1038/NMETH1100
Annegret Kuhn, Martin Herrmann, Susanne Kleber, Maria Beckmann-Welle, Karin Fehsel, Ana Martin-Villalba, Percy Lehmann, Thomas Ruzicka, Peter H. Krammer, Victoria Kolb-Bachofen, Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation Arthritis & Rheumatism. ,vol. 54, pp. 939- 950 ,(2006) , 10.1002/ART.21658
Shyra J. Gardai, Kathleen A. McPhillips, S. Courtney Frasch, William J. Janssen, Anna Starefeldt, Joanne E. Murphy-Ullrich, Donna L. Bratton, Per-Arne Oldenborg, Marek Michalak, Peter M. Henson, Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte Cell. ,vol. 123, pp. 321- 334 ,(2005) , 10.1016/J.CELL.2005.08.032
V A Fadok, D L Bratton, A Konowal, P W Freed, J Y Westcott, P M Henson, Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. Journal of Clinical Investigation. ,vol. 101, pp. 890- 898 ,(1998) , 10.1172/JCI1112
Jakob Dalgaard, Karen J. Beckstrøm, Frode L. Jahnsen, Jan E. Brinchmann, Differential capability for phagocytosis of apoptotic and necrotic leukemia cells by human peripheral blood dendritic cell subsets Journal of Leukocyte Biology. ,vol. 77, pp. 689- 698 ,(2005) , 10.1189/JLB.1204711