The Precision of QSAR Methods For Estimating Intermedia Transfer Factors in Exposure Assessments

摘要: Abstract Dose assessments based on multimedia exposure models require intermedia-transfer factors (ITFs) as input. These relate contaminant concentrations in an environmental medium (the source such air. water, or soil for which measurements are available) to the (personal air, tap and food products) with humans have contact. In this paper, I use QSAR applied partition coefficients between plants, air animal diet lipid tissues case studies characterizing precision of ITF estimations. form basis total dose required realistic exposure/risk assessments. The quantitative relationship ITFs chemical properties developed along estimation errors associated these relationships. Many correlations large that limit their reliability risk assessment. examine contribute estim...