The role of serum tumour markers to aid the selection of lung cancer patients for surgery and the assessment of prognosis

作者: T. Muller , R.J. Marshall , E.H. Cooper , D.A. Watson , D.A. Walker

DOI: 10.1016/0277-5379(85)90238-X

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摘要: We have measured the following ten serum proteins in a sample of 290 patients presenting with possible lung cancer: carcinoembryonic antigen (CEA), alpha 1-acid glycoprotein (AGP), C-reactive protein (CRP), ferritin (FER), prealbumin (PAB), third component complement (C3), immunoglobin E (IgE), 2-pregnancy-associated (PAG), beta 2-microglobulin (beta 2-m) and retinol binding (RBP). It is found that, exception PAG, C3 IgE, there are significant differences between concentrations subsequently diagnosed cancer non-cancer patients. However, who were suitable for surgery do not differ significantly from inoperable The prognostic significance operable also envisaged. In group appears to be useful, whilst AGP RBP indicators group.

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