Refined localization of the Escherichia coli F4ab/F4ac receptor locus on pig chromosome 13
作者： D. Joller , C. B. Jørgensen , H. U. Bertschinger , P. Python , I. Edfors
DOI: 10.1111/J.1365-2052.2009.01881.X
关键词:
摘要: Diarrhoea in newborn and weaned pigs caused by enterotoxigenic Escherichia coli (ETEC) expressing F4 fimbriae leads to considerable losses pig production. In this study, we refined the mapping of receptor locus for ETEC F4ab/F4ac adhesion (F4bcR) joint analysis Nordic Swiss data. A total 236 from a experimental herd, 331 herd 143 performing station were used linkage analysis. Genotyping data six known microsatellite markers, two newly developed markers (MUC4gt HSA125gt) an intronic SNP MUC4 (MUC4-8227) create map. The region F4bcR was interval SW207-S0075 on chromosome 13. most probable position SW207-MUC4 region. order supported physical BAC fingerprint contig Wellcome Trust Sanger Institute. Thus, could be reduced 26 14 Mb.
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