The biology and synthesis of α-hydroxytropolones

作者: Christine Meck , Michael P. D'Erasmo , Danielle R. Hirsch , Ryan P. Murelli

DOI: 10.1039/C4MD00055B

关键词:

摘要: α-Hydroxytropolones are a subclass of the troponoid family natural products that high interest due to their broad biological activity and potential as treatment options for several diseases. Despite this promise, there have been scarce synthetic chemistry-driven optimization studies on molecules. The following review highlights key developments in conducted α-hydroxytropolones date, including few studies. In addition, we provide an overview methods currently available access these This is intended serve resource those interested α-hydroxytropolones, inspire development new strategies could aid pursuit.

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