Visible-Light-Induced Alkoxyl Radical Generation Enables Selective C(sp3)–C(sp3) Bond Cleavage and Functionalizations
作者： Kunfang Jia , Fuyuan Zhang , Hanchu Huang , Yiyun Chen , None
DOI: 10.1021/JACS.5B13066
关键词:
摘要: The alkoxyl radical is an important reactive intermediate in mechanistic studies and organic synthesis; however, its current generation from alcohol oxidation heavily relies on transition metal activation under strong oxidative conditions. Here we report the first visible-light-induced to generate radicals by cyclic iodine(III) reagent catalysis mild reaction β-fragmentation of enables selective C(sp3)–C(sp3) bond cleavage alkynylation/alkenylation reactions with various strained cycloalkanols, for time linear alcohols.
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