Lewis acid catalyzed formation of tetrahydroquinolines via an intramolecular redox process.
作者： Sandip Murarka , Chen Zhang , Marlena D. Konieczynska , Daniel Seidel
DOI: 10.1021/OL802519R
关键词:
摘要: Polycyclic tetrahydroquinolines were prepared by an efficient Lewis acid catalyzed 1,5-hydride shift, ring closure sequence. Gadolinium triflate was identified as a catalyst that is superior to scandium well other acids. An approach toward catalytic enantioselective variant also described.
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