Physiological responses to treadmill exercise and ambient temperature in normal and malignant hyperthermia susceptible pigs.

摘要: Abstract Ten susceptible and ten resistant pigs to malignant hyperthermia were used observe the effects of exercise ambient temperature on selected physiological parameters. Pigs submitted a minute treadmill operating at speed 1.8 km/h inclined 11 degrees. Exercise in first group was an 14 degrees C, second 29 C. The right carotid artery previously cannulated for blood pressure measurements repeated sampling during exercise. Arterial pressure, heart rate, rectal cutaneous temperatures recorded. Levels cortisol, creatine kinase its isoenzymes measured. At caused some adjustments animals; skin cortisol levels increased (P less than 0.05). In pigs, only rate elevated significantly following exertional stress C produced severe marked changes: both swine. also had higher serum total MM isoenzyme 0.05) compared pigs. results indicate that, or thermal stress, undergo more extensive changes do Similar prior slaughter may trigger which would likely result pale, soft exudative myopathy.