Intraductal carcinoma of the breast (208 cases): Clinical factors influencing treatment choice

摘要: Two hundred eight cases of intraductal breast carcinoma (DCIS) were selectively treated; 97 with mastectomy, 96 radiation therapy, and 15 using excisional biopsy only. Mastectomy patients tended to have larger tumors, involved margins, palpable often multifocal tumors. Breast preservation smaller, occult, tumors clear surgical margins. Before 1983, mastectomy was more common; during after common. Comedocarcinomas the most frequent They largest, had highest percentage microinvasion (20%), recurrence rate (8%). Noncomedo DCIS a 1%, one 103 The for comedocarcinomas treated therapy nearly three times higher than those (11% versus 4%). One 164 (0.6%) axillary lymph node dissections yielded positive nodes. Nine recurred: two in group seven conservation (P less 0.1). Eight nine recurrences comedo subtype 0.05). Three developed metastatic disease, whom died. Axillary dissection is unlikely yield nodes not indicated cases. It should be reserved lesions revealing microinvasion. Conservative comedocarcinoma must viewed caution.