Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection

作者: Y M Dennis Lo , Nancy B Y Tsui , Rossa W K Chiu , Tze K Lau , Tse N Leung

DOI: 10.1038/NM1530

关键词:

摘要: … We previously reported the presence of cell-free fetal DNA in the plasma of pregnant … of fetal chromosomal copy number is not yet feasible 10 . An elevation in circulating fetal DNA …

参考文章(27)
J. Kaiser, PRENATAL DIAGNOSIS: An Earlier Look At Baby's Genes Science. ,vol. 309, pp. 1476- 1478 ,(2005) , 10.1126/SCIENCE.309.5740.1476
Zarko Alfirevic, Kate Navaratnam, Faris Mujezinovic, Amniocentesis and chorionic villus sampling for prenatal diagnosis Cochrane Database of Systematic Reviews. ,vol. 9, pp. 0- 0 ,(2017) , 10.1002/14651858.CD003252.PUB2
Christian Jurinke, Paul Oeth, Dirk van den Boom, MALDI-TOF mass spectrometry: a versatile tool for high-performance DNA analysis. Molecular Biotechnology. ,vol. 26, pp. 147- 163 ,(2004) , 10.1385/MB:26:2:147
D. W. Bianchi, A. F. Flint, M. F. Pizzimenti, J. H. Knoll, S. A. Latt, Isolation of fetal DNA from nucleated erythrocytes in maternal blood Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 3279- 3283 ,(1990) , 10.1073/PNAS.87.9.3279
NBY Tsui, SSC Chim, RWK Chiu, TK Lau, EKO Ng, TN Leung, YK Tong, KCA Chan, YMD Lo, None, Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling Journal of Medical Genetics. ,vol. 41, pp. 461- 467 ,(2004) , 10.1136/JMG.2003.016881
Ronald J. Wapner, Invasive prenatal diagnostic techniques. Seminars in Perinatology. ,vol. 29, pp. 401- 404 ,(2005) , 10.1053/J.SEMPERI.2006.01.003
Philippe Anker, Hugh Mulcahy, Maurice Stroun, Circulating nucleic acids in plasma and serum as a noninvasive investigation for cancer: Time for large‐scale clinical studies? International Journal of Cancer. ,vol. 103, pp. 149- 152 ,(2003) , 10.1002/IJC.10791
Enders KO Ng, Nancy BY Tsui, Tze K Lau, Tse N Leung, Rossa WK Chiu, Nirmal S Panesar, Lydia CW Lit, Kam-Wing Chan, YM Dennis Lo, mRNA of placental origin is readily detectable in maternal plasma Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 4748- 4753 ,(2003) , 10.1073/PNAS.0637450100
David J. Amor, Wee Thong Neo, Elizabeth Waters, Helen Heussler, Mark Pertile, Jane Halliday, Health and developmental outcome of children following prenatal diagnosis of confined placental mosaicism Prenatal Diagnosis. ,vol. 26, pp. 443- 448 ,(2006) , 10.1002/PD.1433
Susumu Kido, Noriaki Sakuragi, Mary P. Bronner, Raja Sayegh, Ralph Berger, David Patterson, Jerome F. Strauss, D21S418E Identifies a cAMP-Regulated Gene Located on Chromosome 21q22.3 That Is Expressed in Placental Syncytiotrophoblast and Choriocarcinoma Cells Genomics. ,vol. 17, pp. 256- 259 ,(1993) , 10.1006/GENO.1993.1317