Necrotizing Clostridium difficile Enteritis Complicating Fulminant Colitis

摘要: Abstract Background: Clostridium difficile infections result from an imbalance in normal bacterial flora, allowing C. bacteria overgrowth. Whereas such overgrowth is typically confined to the colon, there have been reports of increasing prevalence involving small bowel, with majority patients presenting a history partial or total colectomy. We present two rare cases necrotizing enteritis complicating fulminant colitis. Case Presentations: A 74-year-old male presented two-week watery diarrhea and escalating abdominal pain without recent antibiotic use. Work-up was significant for leukocytosis, bandemia, lactic acidosis, elevated creatinine. Initial diagnosis treated intravenous fluoroquinolone metronidazole. He deteriorated colectomy bowel resection performed. Final pathology revealed pseudomembranous colitis focal mucosal ische...