LIN, a Novel Type of U-Box/WD40 Protein, Controls Early Infection by Rhizobia in Legumes

摘要: The formation of a nitrogen-fixing nodule requires the coordinated development rhizobial colonization and organogenesis. Based on its mutant phenotype, lumpy infections (lin), LIN functions at an early stage symbiotic process, required for both infection thread growth in root hair cells further primordia. We show that spontaneous nodulation activated by calcium- calmodulin-dependent protein kinase is independent LIN; thus, not necessary From this, we infer predominantly during abortion this process lin mutants leads to suppression development. Here, identify gene Medicago truncatula Lotus japonicus, showing it codes predicted E3 ubiquitin ligase containing highly conserved U-box WD40 repeat domains. Ubiquitin-mediated degradation universal mechanism regulate many biological processes eliminating rate-limiting enzymes key components such as transcription factors. propose regulator component(s) factor signal transduction pathway function correct temporal spatial activity target protein(s).