An effect of ouabain on the superficially-located stores of calcium in cardiac muscle cells
作者： W Nayler
DOI: 10.1016/0022-2828(73)90039-4
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摘要: The effect of ouabain on the amount Ca2+ (detected as 45Ca2+) displaceable by La3+ from 45Ca2+-labelled heart muscle was studied. doses used were restricted to those which evoke a positive inotropic response without contracture. had negative effect. Inotropically-active increased displaced La3+. These results are cited evidence membrane-located site action for ouabain.
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sci-hub.se 参考文章(19)
H BESCH, On a mechanism of action of digitalis Journal of Molecular and Cellular Cardiology. ,vol. 1, pp. 195- 199 ,(1970) , 10.1016/0022-2828(70)90054-4
G Langer, Effects of strophanthidin upon contraction and ionic exchange in rabbit ventricular myocardium: relation to control of active state. Journal of Molecular and Cellular Cardiology. ,vol. 1, pp. 65- 90 ,(1970) , 10.1016/0022-2828(70)90029-5
EARL H. WOOD, RICHARD L. HEPPNER, SILVIO WEIDMANN, Inotropic Effects of Electric Currents Circulation Research. ,vol. 24, pp. 409- 445 ,(1969) , 10.1161/01.RES.24.3.409
K. KUSCHINSKY, H. LÜLLMANN, P. A. ZWIETEN, A comparison of the accumulation and release of 3H-ouabain and 3H-digitoxin by guinea-pig heart muscle. British journal of pharmacology and chemotherapy. ,vol. 32, pp. 598- 608 ,(1968) , 10.1111/J.1476-5381.1968.TB00460.X
C. F. Doggenweiler, S. Frenk, STAINING PROPERTIES OF LANTHANUM ON CELL MEMBRANES Proceedings of the National Academy of Sciences of the United States of America. ,vol. 53, pp. 425- 430 ,(1965) , 10.1073/PNAS.53.2.425
G. A. Langer, J. S. Frank, LANTHANUM IN HEART CELL CULTURE : Effect on Calcium Exchange Correlated with Its Localization Journal of Cell Biology. ,vol. 54, pp. 441- 455 ,(1972) , 10.1083/JCB.54.3.441
A Katz, Increased Ca2+ entry during the plateau of the action potential: A possible mechanism of cardiac glycoside action Journal of Molecular and Cellular Cardiology. ,vol. 4, pp. 87- 89 ,(1972) , 10.1016/0022-2828(72)90100-9
G. A. Langer, Coupling calcium in mammalian ventricle: its source and factors regulating its quantity. Cardiovascular Research. ,vol. 5, pp. 71- 75 ,(1971) , 10.1093/CVR/5.SUPP1.71
Susumu Hagiwara, Shigehiro Nakajima, Differences in Na and Ca Spikes As Examined by Application of Tetrodotoxin, Procaine, and Manganese Ions The Journal of General Physiology. ,vol. 49, pp. 793- 806 ,(1966) , 10.1085/JGP.49.4.793
A. Schwartz, H. Matsui, A. H. Laughter, Tritiated Digoxin Binding to (Na+ + K+)-Activated Adenosine Triphosphatase: Possible Allosteric Site Science. ,vol. 160, pp. 323- 325 ,(1968) , 10.1126/SCIENCE.160.3825.323