Factors Associated With Unreliable Liver Stiffness Measurement and Its Failure With Transient Elastography in the Chinese Population

作者: Grace L‐H Wong , Vincent W‐S Wong , Angel M‐L Chim , Karen K‐L Yiu , Shirley H‐T Chu

DOI: 10.1111/J.1440-1746.2010.06510.X

关键词:

摘要: Background and Aim:  Liver stiffness measurement (LSM) with transient elastography is a non-invasive reliable test for liver fibrosis. However small proportion of patients may have unreliable LSM or failure. The aim the present study was to investigate factors associated failure in Chinese patients. Methods:  We prospectively recruited LSM. Unreliable defined as  30%, success rate < 60%. zero valid shots. Results:  Among 3205 LSM, 371 (11.6%) 88 (2.7%) had failure, respectively. rates started increase when body mass index (BMI) ≥ 28.0 kg/m2. Comparing BMI ≥ 28.0–29.9 kg/m2 versus those BMI ≥ 30.0 kg/m2, (16.4% vs 18.9%; P = 0.62) (11.8% 17.8%; P = 0.16) were similar. BMI ≥ 28.0 kg/m2 most important factor (odds ratio [OR] = 2.9, 95% confidence interval [CI] = 2.1–3.9, P   80 cm women > 90 cm men, another independent risk (OR = 1.3, CI = 1.0–1.6, P = 0.04) (OR = 5.8, CI = 2.9–11.5, P < 0.0001). Conclusion:  central obesity Chinese, these significantly higher extreme BMI.

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