摘要: Zu den haufigen Folgeerkrankungen der Hypertonie gehoren Nierenschaden. In Nieren bewirkt die arterielle sowohl als auch kapillare Veranderungen sowie Entwicklung einer interstitiellen Fibrose. Die systemische oder intraglomerulare Druckerhohung fuhrt zu Albuminurie und Proteinurie, wiederum zur weiteren Schadigung beitragen. Letztlich kann hypertensiv bedingte Nierenschadigung dialysepflichtigen terminalen Niereninsuffizienz fuhren. Metabolische Faktoren wie eine Hyperlipidamie, Hyperurikamie, Hyperhomozysteinamie Insulinresistenz konnen renalen Lasionen potenzieren. Eine konsequente Blutdrucksenkung zusammen mit Behandlung metabolischen Risikofaktoren ist daher von entscheidender Bedeutung, um chronische Nierenschadigung, Faktor Hypertonieverschlechterung angesehen werden muss, verhindern.
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