The Antibiotic and Nonantibiotic Tetracyclines

摘要: The tetracyclines have been used for over 50 years in human health and agricultural veterinary practices, primarily as antibacterial agents. properties the qualitative structure–activity relationships are reviewed along with some of biological effects bacteria other microbial pathogens. More recently, nonantibiotic studied, where they found uses clinically matrix metalloproteinase inhibitors antagonists processes related to inflammation neurodegenerative diseases. also effectors Tet On–Tet Off genetic switch, furthering useful this family significant compounds.