A MAPK Scaffold Lends a Helping Hand
作者： Markus A. Seeliger , John Kuriyan
DOI: 10.1016/J.CELL.2009.03.002
关键词:
摘要: The scaffold proteins of signaling pathways are thought to act as passive tethering devices bringing together catalytic components cascades. Good et al. (2009) now reveal that in the budding yeast protein Ste5 acts an allosteric activator mitogen-activated kinase Fus3, rendering it competent be a substrate for signal transmission.
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