Factors predicting outcome of fungal peritonitis in peritoneal dialysis : analysis of a 9-year experience of fungal peritonitis in a single center

摘要: Fungal peritonitis causes significant morbidity and mortality for patients undergoing continuous ambulatory peritoneal dialysis (CAPD). We retrospectively reviewed 70 episodes of fungal in a single center over the last 9 years 896 CAPD patients. Seventy percent were caused by Candida species, among which 50% parapsilosis. As result peritonitis, 44% died, whereas further failed 14%, requiring change to long-term hemodialysis. Only 37% managed continue CAPD. The remaining 5% either underwent transplantation or lost follow-up. identified factors associated with poor outcome, namely technique failure. presence abdominal pain, bowel obstruction, catheter situ significantly greater mortality. Abdominal antibiotic use within 3 months before complication obstruction In choosing antifungal agents removal, oral fluconazole alone appears equally as effective combined 5-flucytosine species. For species other than Candida, choice therapy needs be individualized, based on sensitivities.