Mechanisms of Polycythemia

作者: John W. Adamson

DOI: 10.1007/978-1-4899-6688-9_16

关键词:

摘要: Polycythemia in man is defined as an increase the hematocrit and hemoglobin concentration above accepted normal values. As such, finding of polycythemia implies increased production erythrocytes. Since red cell governed normally by interaction oxygen (O2) availability, elaboration regulatory hormone, erythropoietin, marrow function, it not surprising that derangements these interrelationships account for virtually all causes polycythemia. This chapter summarizes briefly various aspects regulation focuses on those identified mechanisms which lead to

参考文章(72)
W. J. MITUS, PETER GALBRAITH, MOHAN GOLLERKERI, K. TOYAMA, Brenda Dorson-Halfond, EXPERIMENTAL RENAL ERYTHROCYTOSIS. I. EFFECTS OF PRESSURE AND VASCULAR INTERFERENCE. Blood. ,vol. 24, pp. 343- 355 ,(1964) , 10.1182/BLOOD.V24.4.343.343
Arthur L. Sagone, Thomas Lawrence, Stanley P. Balcerzak, Effect of Smoking on Tissue Oxygen Supply Blood. ,vol. 41, pp. 845- 851 ,(1973) , 10.1182/BLOOD.V41.6.845.845
Nathaniel I. Berlin, Diagnosis and classification of the polycythemias Seminars in Hematology. ,vol. 12, pp. 339- 351 ,(1975) , 10.5555/URI:PII:0037196375900098
C. Z�rcher, J. A. Loos, H. K. Prins, Hereditary High ATP Content of Human Erythrocytes Folia haematologica (Germany). ,vol. 23, pp. 549- 556 ,(1965) , 10.1159/000384309
John V. Weil, Gail Jamieson, Donald W. Brown, Robert F. Grover, The red cell mass-arterial oxygen relationship in normal man Journal of Clinical Investigation. ,vol. 47, pp. 1627- 1639 ,(1968) , 10.1172/JCI105854
John W. Adamson, George Stamatoyannopoulos, Stella Kontras, Andre Lascari, James Detter, Recessive familial erythrocytosis: aspects of marrow regulation in two families. Blood. ,vol. 41, pp. 641- 652 ,(1973) , 10.1182/BLOOD.V41.5.641.641
PAUL HELLER, HYMAN G. WEINSTEIN, VINCENT J. YAKULIS, IRA M. ROSENTHAL, Hemoglobin MKankakee, A New Variant of Hemoglobin M Blood. ,vol. 20, pp. 287- 301 ,(1962) , 10.1182/BLOOD.V20.3.287.287
Letter: Bone-marrow responses in polycythemia vera. The New England Journal of Medicine. ,vol. 290, pp. 1382- ,(1974) , 10.1056/NEJM197406132902419
Wasserman Lr, The treatment of polycythemia vera. Seminars in Hematology. ,vol. 13, pp. 57- 78 ,(1976)