Antiphospholipid antibodies in neonates with stroke—a unique entity or variant of antiphospholipid syndrome?:
作者： Y Berkun , MJ Simchen , T Strauss , S Menashcu , S Padeh
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摘要: ObjectiveYB current affiliation: Department of Pediatrics, Hadassah-Hebrew University Medical Center, Mount Scopus, IsraelYB and MJS contributed equally to the study should be regarded as joint first authors on this manuscript.Antiphospholipid syndrome (APS) may present with thrombosis persistently elevated titers antiphospholipid antibodies (aPL) in neonatal period. Our aim was investigate course impact aPL a cohort infants presenting either perinatal arterial ischemic stroke (PAS) or cerebral sinus vein (CSVT) during period.Study designSixty-two clinically radiologically confirmed PAS CSVT period underwent thrombophilia workup that included Factor V Leiden (FVL), PII20210A mutation, MTHFR 677T polymorphism, protein C, S, namely circulating lupus anticoagulant (CLA), anticardiolipin (aCL) anti-β2-glycoprotein-1 (β2GP1). Mothers also ...
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