Fed-Batch Cultures: Idealized Reactors and Fed-Batch Reactors

摘要: Prior to presenting the principles of fed-batch operations, it is instructive review quickly various forms idealized reactors: batch, continuous, and semi-batch reactors. This will help in understanding simplest form operation as equivalent a continuous-stirred tank reactor (CSTR) followed by batch (BR). It becomes simple easy understand bioreactor mimicking dynamic CSTR BR maximize reaction rate or product yield. In other words, for single reaction, sufficient condition superior performance that and/or yield show maximum decrease with substrate concentration. Basically, preferred when main side exhibits if more sensitive than reactant concentrations. Fed-batch operations can take advantage sensitivity reactions (yield) manipulating (reactant) concentration reactor.