Mannich–Michael versus formal aza-Diels–Alder approaches to piperidine derivatives
作者： P. Ricardo Girling , Takao Kiyoi , Andrew Whiting
DOI: 10.1039/C0OB00996B
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摘要: A review into the aza-Diels–Alder reaction, mainly concentrating on literature examples that form piperidin-4-ones from reaction of imines and electron rich dienes or enones, either through a Lewis acidic/Bronsted acid approach use an organocatalyst. This questions whether mechanism is step wise as opposed to concerted when using oxygenated dienes.
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