Descriptive epidemiology of persistent diarrhoea among young children in rural northern India.

摘要: In order to determine the descriptive epidemiology of persistent diarrhoea in rural northern India, a cohort 963 children aged 0-71 months was followed prospectively for 12 through weekly household visits. The incidence 6.3 per 100 child-years among those months, and highest (31 child-years) 0-11 months. There were no significant sex-related differences disease, overall seasonal distribution acute similar. persistence diarrhoeal symptoms significantly correlated with higher initial mean stool frequency (P less than 0.01) passage gross blood stools 0.001). Persistent an important problem during first 2 years life. Established enteric pathogens isolated illness 46.4% 55.4% episodes. Pathogens episodes included enterotoxigenic Escherichia coli (ETEC 9.3%), Salmonella spp. (4.7%), as well campylobacter Shigella (2.3%), Entamoeba histolytica rotavirus (2.3%). Similar proportions these also diarrhoea. Multiple 7% 5% E. that manifested aggregative adherence (EAEC-A) more common (34.9% versus 12.3%) 0.01), faecal excretion EAEC-A associated episode.