Method and composition for crystallizing a family c gpcr
作者： Brian Kobilka
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摘要: Certain embodiments provide a method for crystallizing GPCR. The may employ fusion protein comprising, from N-terminus to C-terminus: a) first portion of family C G-protein coupled receptor (GPCR), wherein the comprises TM1, TM2 and TM3, regions GPCR; b) stable, folded insertion; c) second GPCR, TM4, TM5 TM6 TM7
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