Preclinical Magnetic Resonance Imaging in Mouse Cancer Models

摘要: The use of magnetic resonance imaging (MRI) in humans and animal models has been rapidly growing. MRI provides high spatial resolution, excellent tissue contrast, outstanding definition the anatomical structure normal organs tumors. Because does not require genetically encoded reporters, it can be used for tumor surveillance assessment treatment effects a variety mouse cancer models. systems preclinical typically operate at higher field strength, ranging from 4.7 to 15 T, as opposed clinical scanners, which range 1.5 3 T. strength dedicated resolution signal-to-noise ratios. requires optimization numerous parameters, including pulse sequences radio frequency coils. Here, we describe protocol covering general procedures MRI.