X-Linked Vacuolated Myopathy
作者： Karl Rouger , Jean-Pierre Louboutin , Marcello Villanova , Yan Cherel , Michel Fardeau
DOI: 10.1016/S0002-9440(10)63976-4
关键词:
摘要: The presence and the distribution of tumor necrosis factor-α, interferon-γ, p65 subunit nuclear factor-κB, molecules known to induce synergistically mediate major histocompatibility complex (MHC) class I expression, were determined in muscle sections from control X-linked vacuolated myopathy patients. MHC colocalized with factor-α as well p65, most membrane attack complex- and/or calcium-positive fibers myopathy. These results suggest that expression could be induced by interferon-γ partly mediated factor-κB.
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