Two Cases of Vancomycin-Resistant Enterococcus faecium Bacteremia With Development of Daptomycin-Resistant Phenotype and its Detection Using Oxford Nanopore Sequencing.
作者： Zulema Udaondo , Piroon Jenjaroenpun , Thidathip Wongsurawat , Erik Meyers , Courtney Anderson
DOI: 10.1093/OFID/OFAA180
关键词:
摘要: In this work, we report 2 cases of vancomycin-resistant Enterococcus faecium bacteremia with development daptomycin resistance in patients acute myeloid leukemia and myelodysplastic syndrome. Mutations related to daptomycin-nonsusceptible phenotype liaSR genes were found all strains the study, including those a minimum inhibitory concentration <1 µg/mL collected before therapy. Epidemiological investigation using core genome single nucleotide polymorphism multilocus sequence typing revealed clonality isolates. conclude that real-time sequencing clinical isolates can provide rapid access timely information on daptomycin-resistant genotypes would help clinicians speed up optimize selection antibiotic for treatment.
oup.com
sci-hub.st 参考文章(20)
Hadley Wickham, ggplot2: Elegant Graphics for Data Analysis ,(2009)
Alexandre P Francisco, Miguel Bugalho, Mário Ramirez, João A Carriço, Global optimal eBURST analysis of multilocus typing data using a graphic matroid approach BMC Bioinformatics. ,vol. 10, pp. 152- 152 ,(2009) , 10.1186/1471-2105-10-152
Keith A Jolley, Martin CJ Maiden, BIGSdb: Scalable analysis of bacterial genome variation at the population level BMC Bioinformatics. ,vol. 11, pp. 595- 595 ,(2010) , 10.1186/1471-2105-11-595
Andrew G McArthur, Nicholas Waglechner, Fazmin Nizam, Austin Yan, Marisa A Azad, Alison J Baylay, Kirandeep Bhullar, Marc J Canova, Gianfranco De Pascale, Linda Ejim, Lindsay Kalan, Andrew M King, Kalinka Koteva, Mariya Morar, Michael R Mulvey, Jonathan S O'Brien, Andrew C Pawlowski, Laura JV Piddock, Peter Spanogiannopoulos, Arlene D Sutherland, Irene Tang, Patricia L Taylor, Maulik Thaker, Wenliang Wang, Marie Yan, Tennison Yu, Gerard D Wright, None, The Comprehensive Antibiotic Resistance Database Antimicrobial Agents and Chemotherapy. ,vol. 57, pp. 3348- 3357 ,(2013) , 10.1128/AAC.00419-13
Alexey Gurevich, Vladislav Saveliev, Nikolay Vyahhi, Glenn Tesler, QUAST: quality assessment tool for genome assemblies Bioinformatics. ,vol. 29, pp. 1072- 1075 ,(2013) , 10.1093/BIOINFORMATICS/BTT086
JOSE MUNITA SEPULVEDA, Diana Panesso, Lorena Diaz, Truc T Tran, Jinnethe Reyes, Audrey Wanger, Barbara E Murray, Cesar A Arias, None, Correlation between Mutations in liaFSR of Enterococcus faecium and MIC of Daptomycin: Revisiting Daptomycin Breakpoints Antimicrobial Agents and Chemotherapy. ,vol. 56, pp. 4354- 4359 ,(2012) , 10.1128/AAC.00509-12
H. Li, B. Handsaker, A. Wysoker, T. Fennell, J. Ruan, N. Homer, G. Marth, G. Abecasis, R. Durbin, , The Sequence Alignment/Map format and SAMtools Bioinformatics. ,vol. 25, pp. 2078- 2079 ,(2009) , 10.1093/BIOINFORMATICS/BTP352
Anton Bankevich, Sergey Nurk, Dmitry Antipov, Alexey A. Gurevich, Mikhail Dvorkin, Alexander S. Kulikov, Valery M. Lesin, Sergey I. Nikolenko, Son Pham, Andrey D. Prjibelski, Alexey V. Pyshkin, Alexander V. Sirotkin, Nikolay Vyahhi, Glenn Tesler, Max A. Alekseyev, Pavel A. Pevzner, SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing Journal of Computational Biology. ,vol. 19, pp. 455- 477 ,(2012) , 10.1089/CMB.2012.0021
Lorena Diaz, Truc T Tran, Jose M Munita, William R Miller, Sandra Rincon, Lina P Carvajal, Aye Wollam, Jinnethe Reyes, Diana Panesso, Natalia L Rojas, Yousif Shamoo, Barbara E Murray, George M Weinstock, Cesar A Arias, None, Whole-Genome Analyses of Enterococcus faecium Isolates with Diverse Daptomycin MICs Antimicrobial Agents and Chemotherapy. ,vol. 58, pp. 4527- 4534 ,(2014) , 10.1128/AAC.02686-14
Anthony M. Bolger, Marc Lohse, Bjoern Usadel, Trimmomatic: a flexible trimmer for Illumina sequence data Bioinformatics. ,vol. 30, pp. 2114- 2120 ,(2014) , 10.1093/BIOINFORMATICS/BTU170