Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes
作者： Noelia Nebot , Severine Crettol , Fabrizio D'Esposito , Bruce Tattam , David E Hibbs
DOI: 10.1111/J.1476-5381.2010.00946.X
关键词:
摘要: … The present study evaluated the possibility that multiple CYPs … and other drug metabolizing CYPs were assessed. … oxidation of CYP3A and CYP2C8 substrates and the inhibition of N-…
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