作者: Cyrill Bussy , Laura Methven , Kostas Kostarelos
DOI: 10.1016/J.ADDR.2013.10.008
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摘要: Carbon nanotubes may enter into the bloodstream and interact with blood components indirectly via translocation following unintended exposure or directly after an intended administration for biomedical purposes. Once introduced systemic circulation, will encounter various proteins, biomolecules cells which have specific roles in homeostasis of circulatory system. It is therefore essential to determine whether those interactions lead adverse effects not. Advances understanding how carbon complement system, red hemostatic system are reviewed this article. While many studies on nanotube health risk assessment their applications appeared last few years, reports hemocompatibility these nanomaterials remain surprisingly limited. Yet, defining hemotoxicological profile a mandatory step toward development clinically-relevant medications contrast agents based nanotubes.