The role of rheology of polymer solutions in predicting nanofiber formation by electrospinning

摘要: Abstract Electrospun polymer nanofibers are gaining increasing importance in tissue engineering, wound dressing and drug delivery. Here, we present a thorough rheological study of solutions the bulk at interface to find correlations between those properties electrospinnability morphology resultant nanofibers. Our results indicate that blended chitosan or alginate with poly(ethylene oxide) (PEO) appropriate for electrospinning when they form conductive, unstructured fluids displaying plasticity, rather than elasticity, interface. The interfacial parameters three orders magnitude lower bulk. We demonstrate first time interfacial, bulk, show improved correlation can be used predict success process. Using samples homologous compositions, different groups identified smooth However, provide complimentary information. determined by concentration directly affect jet initiation, while behaviour determines continuation fibre formation. propose indispensible tools design experiments.