Impaired fasting glucose or impaired glucose tolerance. What best predicts future diabetes in Mauritius

摘要: OBJECTIVE: To determine if impaired fasting glucose (IFG; plasma level 6.1-6.9 mmol/l) can predict future type 2 diabetes as accurately does tolerance (IGT; 2-h 7.8-11.0 mmol/l). RESEARCH DESIGN AND METHODS: A longitudinal population-based study was performed with surveys in 1987 and 1992 on the island of Mauritius, assessing status by oral test. total 3,717 subjects took part both surveys. Of these subjects, 3,229 were not diabetic formed basis this study. RESULTS: At baseline, there 607 IGT 266 IFG. There 297 who developed 1992. For predicting progression to diabetes, sensitivity, specificity, positive predictive values 26, 94, 29% for IFG 50, 84, 24% IGT, respectively. Only 26% that progressed predicted their values, but a further 35% could be identified also considering IGT. The sensitivities 37% men 66% women, CONCLUSIONS: These data demonstrate higher sensitivity over diabetes. Screening criteria alone would identify fewer people subsequently progress than