Značenje Dermatophagoides pteronyssinus-a u nastanku i pogoršanju atopijskog dermatitisa

摘要: Sixty one patients, (m:24, f:3, mean age: 43,33 years, range:18 to 65 years), with atopic dermatitis were involved in the study. The control group consisted of thirty subjects (m:13 f: 17, 48,63 range: 25 without personal or family history of atopy. aim study evaluate roleof Dp 1 AD patients using: total serum IgE, specific serum IgE D p1, skin prick test, and atopy „patch“ test using Dp1 as allergen, (increasing doses from 3000 BU/ml, 10000, 20000 30000 BU/ml). According our results 18% (11/61) have positive „late reactions“ and „immediate allergic“ reaction 29,5% (18/61) was positive. It is concluded that is important „trigger“ factor those patients. APT, SPT and sIgE, valuable which can detect factor(s) patients. It founad sIgE has no correlation remission exacerbation AD. SIT represents only curative treatment allergy, she restores disturbed balance Tregs and T effector cells allergic In presented a subgroup (n: 15, m:4, f:11) received SIT (Dp 1) for at least three years. According does not decrease APT reactivity, so this not estimating success. Early oneset (up 2 years old), precedes development rhinitis allergic asthma childhood later. More noted „mixed“