Adverse Prognostic Value of Persistent Office Blood Pressure Elevation in White Coat Hypertension

摘要: Stratification of cardiovascular risk is fundamental importance in white coat hypertension (WCH) to identify individuals need closer follow-up and perhaps antihypertensive drug treatment. In subjects representative the general population Monza (Italy), all-cause mortality was assessed >16 years stable unstable WCH individuals, that is, those whom ambulatory blood pressure (BP) normality associated with a persistent or nonpersistent office BP elevation at 2 consecutive visits, respectively. Data were compared from an entirely normotensive group, normality. Compared death not significantly different WCH, whereas increased also when data adjusted for baseline confounders, including (hazard ratio, 16; P=0.001 1.92; P=0.02 death). At multivariable analysis, among factors independently predicting death, results superimposable use population-derived guidelines-derived cutoff values (125/79 130/80 mm Hg, respectively). Thus, only persistently elevated does reflect existence abnormal long-term risk. This means prognostically relevant repeated collection its clinically important better define patient