Chronic mood disorders in depressed outpatients

作者: Bruce J. Rounsaville , Diane Sholomskas , Brigitte A. Prusoff

DOI: 10.1016/0165-0327(80)90007-5

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摘要: Abstract The current study was devised to assess the utility of Research Diagnostic Criteria (RDC) categories used classify minor mood disorders. Similar are be in APA's and Statistical Manual, 3rd edition. patient sample consisted 64 consecutive admissions a double-blind trial amitriptyline, perphenazine combination as treatment for depression. Patients who met RDC episode major depressive disorder were given 4 weeks pharmacotherapy treatment. Chronic disorders also assessed using criteria. This evaluation revealed that only 34% criteria an alone, while 36% intermittent disorder, 14% cyclothymic personality 16% labile addition being episode. These diagnostic subgroups compared on demographic characteristics, childhood history, psychiatric presenting patterns symptoms social functioning, response Differences noted symptom levels residual impairment. However, there no differential brief course antidepressant patients with without chronic Most showed improvement during Thus, presence does not appear contraindication use medication currently experiencing

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