Modified Talairach landmarks.

摘要: Brain atlas-assisted operations, such as targeting in stereotactic and functional neurosurgery, localisation analysis metanalysis human brain mapping, or structure segmentation labelling neuroradiology, highly depend on the accurate of landmarks used for atlas-to-data registration. One practical widely registration methods is Talairach proportional grid system transformation based landmarks. However, there are several problems associated with original In Talairach-Tournoux atlas, some not available locations others contradict their definitions. When dealing patient-specific data, definitions constructive enough make identification time consuming. Moreover, an inconsistency between grid. The modified landmarks, conceptually equivalent to introduced here. They have advantages overcome limitations Three various intercommissural distances defined: central, internal, tangential, formulas determining lengths errors derived. An efficient method calculating cortical proposed. internal distance closest distance. Its relative error only 0.5%, opposed central tangential resulting high (about 10%) errors. On other hand, result a maximum displacement at cortex amounting about 11 mm while gives 1 error. sensitivity actual location plane reaching above 10%. below 0.5%. Each needs three coordinates its that requires availability two two-dimensional projections, generation which computationally expensive. A landmark identified single, one-dimensional projection. facilitate rapid automated calculation give more flexibility use specific applications. most suitable provide accuracy subcortical structures. mapping research, has be achieved line superior. Human may benefit from minimising due positioning. required both structures should used.