Olfactory Reception: From Signal Modulation to Human Genome Mapping
作者： Nissim Ben-Arie , Michael North , Miriam Khen , Ruth Gross-Isseroff , Naomi Walker
DOI: 10.1007/978-4-431-68355-1_54
关键词:
摘要: Olfactory science has evolved into a comprehensive molecular definition brought about by the realization that broad odorant spectra may still be compatible with receptor genes encoding stereospecific proteins [1–3]. Evidence for existence of specific reception pathways arose discovery G-protein-coupled second messenger transduction cascades in olfactory ciliary membranes [4–6]. Subsequently, family hundreds receptors, first proposed based on available biochemical data [7–9], became reality cloning receptors (ORs) several vertebrate species [10–12]. It is when this understanding combined human psychophysics and genome analysis, better picture function will emerge.
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