Construction of high surface potential polypyrrole nanorods with enhanced antibacterial properties
作者： Wenhao Zhou , Ling Lu , Dafu Chen , Zhengao Wang , Jinxia Zhai
DOI: 10.1039/C7TB03085A
关键词:
摘要: Conductive polymers (CPs) are frequently used as neural and osteogenic implants for signal recording electrical stimulation due to their electroactive good biocompatibility. However, these often fail bacterial infection. In this research, a novel nano-functionalized polypyrrole (PPy) with high surface potential was electrochemically developed improve the antibacterial properties of CPs. Sulfosalicylic acid (SSA)—a biomolecule abundant negatively charged functional groups—was introduced not only successfully assist in assembly Py micelles into extracellular matrix mimetic nanostructure, but also modulate PPy. Scanning Kelvin probe microscopy (SKPM) results confirm increased positive charges on SSA-assisted PPy (PPy/SSA nanorod irregular PPy/SSA film) relative PPy/Cl film. Plate colony-counting experiments that has excellent The higher rate nanorods suggests synergistic effect via structure induced by dopants. Cytotoxicity testing demonstrates samples were nontoxic cells. Our work provides an effective way develop
rsc.org
sci-hub.se 参考文章(42)
L. Pérez, M.R. Infante, R. Pons, C. Morán, P. Vinardell, M. Mitjans, A. Pinazo, A synthetic alternative to natural lecithins with antimicrobial properties. Colloids and Surfaces B: Biointerfaces. ,vol. 35, pp. 235- 242 ,(2004) , 10.1016/J.COLSURFB.2004.03.014
Baolin Guo, Lidija Glavas, Ann-Christine Albertsson, Biodegradable and electrically conducting polymers for biomedical applications Progress in Polymer Science. ,vol. 38, pp. 1263- 1286 ,(2013) , 10.1016/J.PROGPOLYMSCI.2013.06.003
Rylie A. Green, Nigel H. Lovell, Laura A. Poole-Warren, Cell attachment functionality of bioactive conducting polymers for neural interfaces Biomaterials. ,vol. 30, pp. 3637- 3644 ,(2009) , 10.1016/J.BIOMATERIALS.2009.03.043
In Young Kim, Suhye Park, Hyunseok Kim, Sungsu Park, Rodney S. Ruoff, Seong-Ju Hwang, Strongly-coupled freestanding hybrid films of graphene and layered titanate nanosheets: An effective way to tailor the physicochemical and antibacterial properties of graphene film Advanced Functional Materials. ,vol. 24, pp. 2288- 2294 ,(2014) , 10.1002/ADFM.201303040
Mei Li, Wenguang Li, Jun Liu, Jinshui Yao, Preparation and characterization of PPy with methyl orange as soft template Journal of Materials Science: Materials in Electronics. ,vol. 24, pp. 906- 910 ,(2013) , 10.1007/S10854-012-0847-X
Richard Balint, Nigel J. Cassidy, Sarah H. Cartmell, Conductive polymers: towards a smart biomaterial for tissue engineering. Acta Biomaterialia. ,vol. 10, pp. 2341- 2353 ,(2014) , 10.1016/J.ACTBIO.2014.02.015
Ronald S. Flannagan, Gabriela Cosío, Sergio Grinstein, Antimicrobial mechanisms of phagocytes and bacterial evasion strategies Nature Reviews Microbiology. ,vol. 7, pp. 355- 366 ,(2009) , 10.1038/NRMICRO2128
Camelia Ungureanu, Simona Popescu, Gabriela Purcel, Vlad Tofan, Marian Popescu, Aurora Sălăgeanu, Cristian Pîrvu, None, Improved antibacterial behavior of titanium surface with torularhodin–polypyrrole film Materials Science and Engineering: C. ,vol. 42, pp. 726- 733 ,(2014) , 10.1016/J.MSEC.2014.06.020
Victoria J. Gelling, Niteen Jadhav, Christopher A. Vetter, The effect of polymer morphology on the performance of a corrosion inhibiting polypyrrole/aluminum flake composite pigment Electrochimica Acta. ,vol. 102, pp. 28- 43 ,(2013) , 10.1016/J.ELECTACTA.2013.03.128
Alessio Varesano, Annalisa Aluigi, Luca Florio, Riccardo Fabris, Multifunctional cotton fabrics Synthetic Metals. ,vol. 159, pp. 1082- 1089 ,(2009) , 10.1016/J.SYNTHMET.2009.01.036