Compositions and methods for inhibiting tumor development caused by chemotherapy induced senescence

作者: Corine Bertolotto-Ballotti , Robert Ballotti , Sandy Giuliano , Mickael Ohanna

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摘要: The present invention relates to products and compositions containing (i) a chemotherapeutic agent (ii) at least an active compound chosen from CCL2 inhibitors, CCR2 NF-κB PARP-1 inhibitors ATM as combined preparation for simultaneous, separate or sequential use inhibiting tumor development caused by cell senescence induced said agent. also refers method monitoring the response of patient suffering cancer, predicting size evolution and/or onset metastasis in cancer.

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