Synthesis of difluoroalkyl-γ-butyrolactones from iododifluoromethyl ketones and 4-pentenoic acids
作者： Jie-Xiong Wang , Jing-Jing Wu , Heng Chen , Shao-Wu Zhang , Fan-Hong Wu
DOI: 10.1016/J.CCLET.2015.07.007
关键词:
摘要: Abstract A convenient and efficient approach for difluoroalkyl-containing γ -butyrolactones via the radical addition reaction of iododifluoromethyl ketones with 4-pentenoic acids initiated by AIBN in CH 3 CN at 60 °C was reported. Various δ -valerolactones were also synthesized under this conditions.
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