A coating employing an anti-thrombotic conjugate

摘要: A biodegradable antithrombotic conjugate having heparin and other anti-thrombotic moieties are introduced as side chains to the polymer backbone modified by a click chemistry reaction. Various bioabsorbable monomers dimers such valerolactone may be used in monomer derivation, homo- co-polymerization, conjugation with biologically active molecule chemistry. coating comprising biocompatible is applied at least portion of an implantable device prevent or reduce formation thrombosis on surface device. first sub-layer prepared mixing polymeric material agent solvent, thereby forming homogeneous solution. second outer layer present over inner drug-containing layers using, for example, dip spray process.